CareerPlan

Portfolio & Program Management Director

Boston, MA, USFull-time$162k–$243k2026-11-02 → 2026-11-09
Hybrid

Core

Strategic and operational leadership across a portfolio of cross-functional Research programs and projects, spanning early research through candidate preclinical development.

Role type

Senior IC portfolio and program management director

Builds

Integrated portfolio insights, prioritization, strategic decision-making, and execution of critical site and program objectives

Domain

Biotechnology / Pharmaceutical drug discovery and early development

Required skills

Portfolio planning, strategic decision-making, cross-functional team leadership, risk analysis, decision analysis, contingency planning, resource allocation, budgeting, stakeholder management, storytelling, team coaching

Preferred skills

Advanced degree in Life Sciences, experience in drug discovery and early development, knowledge of Vertex Core Values

Technologies

Project and portfolio management tools and methods

Responsibilities

Lead portfolio planning and strategic decision-making; oversee research programs from early research to preclinical development; drive cross-functional project execution; manage resource constraints and budgeting; identify and mitigate risks; communicate complex topics to stakeholders; build and manage PM staff

Seniority

Senior, hands-on IC with line management responsibilities