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Senior Director, Project & Portfolio Management

South San Francisco, CA💼 Full-time💰 $264,000–$264,000🗓 2026-01-09 → 2026-09-26

Core

Build an AI-forward Project & Portfolio Management organization to partner with therapeutic and operations teams in advancing a high-value portfolio of drug candidates into the clinic for neurological, ophthalmological, and metabolic indications.

Role type

Senior Director, Project & Portfolio Management

Builds

Integrated project plans spanning research, discovery, clinical development, software engineering, and data science; agentic AI project management, decision, and resource allocation tools.

Domain

Biotechnology / Pharmaceutical R&D / Drug Discovery

Deliverable

production ML models | product features | dashboards & analysis

Required skills

Project portfolio leadership, cross-functional matrix team management, drug development lifecycle knowledge, translational stage expertise, CMC workflows, clinical development (IND to Phase 2), strategic planning, resource allocation, risk management, governance setup, complex problem solving.

Preferred skills

Agentic workflow design, portfolio planning reviews, disease area strategy (metabolism/neuroscience/ophthalmology), executive communication, startup adaptability.

Technologies

Project management tools, critical path analysis software, scenario planning tools, budget management software.

Responsibilities

Develop rightsized project strategies with project team leaders; execute integrated project plans with clear timelines; establish agentic AI project management and resource allocation methodologies; lead matrix team meetings for collaboration and alignment; resolve complex problems and manage project scope, deliverables, and risks.

Seniority

Senior Director, strategic leadership & hands-on execution

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