Senior Director, DMPK
Core
Lead Drug Metabolism and Pharmacokinetics (DMPK) activities to advance drug discovery and development from early discovery to marketing approval, optimizing ADME properties and managing cross-functional project teams.
Role type
Senior Director, DMPK (Leadership & Strategy)
Builds
Drug discovery and development programs for serious unmet medical needs
Domain
Pharmaceutical R&D, Drug Metabolism and Pharmacokinetics (DMPK)
Required skills
DMPK strategy & portfolio management, ADME optimization, in vitro/in vivo study design, regulatory document preparation, team leadership & mentoring, budget & resource planning, cross-functional collaboration
Preferred skills
AI adoption in drug discovery, multi-therapeutic area experience
Technologies
in vitro tools, in vivo models, bioanalysis platforms, PK prediction software
Responsibilities
Serve as DMPK functional lead on multidisciplinary project teams; Collaborate with medicinal chemists to design strategies avoiding ADME liabilities; Critically evaluate and interpret DMPK data; Prepare regulatory documents (INDs, Investigator Brochures); Develop team strategy aligned with global goals; Manage scientific and business activities; Represent DMPK at governance committees; Mentor personnel and resolve conflicts; Construct resourcing plans and manage budgets; Ensure compatibility with regulatory standards.
Seniority
Senior Director, strategic leadership & mentorship