VP, Disease Business Unit General Manager, US
Core
VP U.S. General Manager accountable for end-to-end business performance, P&L, and strategic priorities for a designated pharmaceutical Business Unit in the US.
Role type
VP, General Manager (Commercial)
Builds
Integrated U.S. Business Unit operations and future innovation pipelines
Domain
Biotechnology / Pharmaceuticals
Required skills
P&L management, commercial leadership, cross-functional leadership, strategic planning, budget management, succession planning, stakeholder engagement, regulatory compliance, market access, lifecycle management
Preferred skills
Portfolio management, enterprise franchise leadership, advocacy group engagement, policy engagement
Technologies
None stated
Responsibilities
Own full P&L responsibility for the U.S. designated Business Unit; Lead an established commercial organization with direct reports across Sales and Marketing; Drive cross-functional leadership across Market Access, Patient Services, Analytics, Commercial Operations, Medical Affairs, R&D, Manufacturing, Legal, Regulatory, Government Affairs, and Patient Advocacy; Ensure continued excellence in launch execution for future indication expansions; Develop and maintain a high-performing leadership bench with strong succession planning; Serve as enterprise steward of Vertex's designated therapeutic area franchise in the U.S.; Lead the organization through the dynamics of a highly penetrated, mature market; Partners with Medical Affairs and Patient Services to ensure patient-centric engagement models; Maintain trusted relationships with the Disease communities including advocacy organizations and treatment centers; Own the U.S. revenue forecast, expense management, and resource allocation; Champions a culture of operational rigor, continuous improvement, and ethical leadership
Seniority
VP, Executive
