Biomarkers Senior Research Lab Scientist (Ligand Binding Assays)
Core
Develop and optimize ligand binding assays (immunoassays, ELISA) for novel biomarkers in human biofluids and tissues to serve as endpoints in clinical trials.
Role type
Senior Research Lab Scientist (Ligand Binding Assays)
Builds
Validated biomarker assays for clinical development
Domain
Biotechnology / Clinical Development / Biomarker Research
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Ligand binding assay development and validation, Immunoassay design, ELISA, Western blot, Protein labeling and quantification, Molecular biology techniques, Cell biology techniques, GLP/GCP compliance, Troubleshooting assay development
Preferred skills
Cell culture and cell-based assays, Genomic assays (qPCR, ddPCR, NGS), Flow cytometry, CRO assay transfer, Translational medicine strategy
Technologies
ELISA, Western blot, qPCR, ddPCR, NGS, Flow cytometry
Responsibilities
Design and execute method development for innovative biomarker assays, Evaluate assay feasibility in biological matrices, Troubleshoot technical challenges in assay development and validation, Generate and analyze experimental data, Partner with CROs for assay transfer and validation, Present results to internal stakeholders
Seniority
Senior, hands-on IC