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Stem Cell Principal Research Scientist, T1D Discovery Biology

Boston, MA💼 Full-time💰 $147,200–$147,200🗓 2026-06-02 → 2026-07-31

Core

Scientific leadership and ownership of stem cell differentiation, characterization, and assay strategies for T1D discovery biology programs.

Role type

Principal Research Scientist (Stem Cell Biology)

Builds

Stem cell-derived cellular models and differentiation platforms for preclinical and IND-enabling objectives

Domain

Biotechnology / Stem Cell Biology / Type 1 Diabetes

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Pluripotent stem cell culture, directed differentiation, functional assays, molecular assays, imaging-based assays, quantitative data analysis, experimental strategy definition, technical roadmap planning, advanced troubleshooting, methods development, scientific mentorship, patent filing, invention disclosure

Preferred skills

Python scripting for data analysis, high-throughput cell culture systems, automated cell-based assay systems, Benchling or ELN/LIMS systems

Technologies

Python, Benchling, ELN, LIMS

Responsibilities

Provide scientific leadership and ownership of stem cell-derived cellular models and assay systems; Define experimental strategy and technical roadmaps for complex differentiation challenges; Distill multidimensional datasets into actionable recommendations for program decisions; Lead development of robust quantitative experimental platforms integrating biology and computational analysis; Drive advanced troubleshooting and methods development for stem cell differentiation; Serve as scientific point of accountability in cross-functional discussions; Contribute to invention disclosures, patent filings, and publications; Provide scientific mentorship and technical direction to junior scientists

Seniority

Principal, hands-on IC with strategic influence and team leadership

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