Principal Scientist – Analytics Team Lead
Core
Lead a team of analytics experts in Physical Chemistry Analytics (PCA) and Mass Spectrometry (MS) to evaluate the developability of biotherapeutic modalities (antibodies, gene therapies, ADCs) and ensure material quality for clinical transition.
Role type
Principal Scientist I/II, Team Lead (Analytics)
Builds
Biotherapeutic modalities (mAbs, fusion proteins, AAVs, Lentiviruses, CAR-Ts) for clinical development (via careerplan.io/jobs/REQ-10082679-1-principal-scientist-analytics-team-lead-at-novartis)
Domain
Biopharmaceuticals / Physical Chemistry Analytics
Required skills
Mass Spectrometry (MS), Chromatography (SEC, HIC, IEX, RPC), Capillary Electrophoresis (cIEF, CZE), Light Scattering (DLS, MALS), LC-MS techniques (Intact, Peptide Mapping, Glycan analysis), Instrument Management (Orbitraps, QTOFs), Team Leadership, Project Management, Data Analysis
Preferred skills
CDMS interpretation for AAV analysis, Novel instrumentation evaluation, Application development for biologics
Technologies
Orbitraps, QTOFs, SEC-MS, CE-MS, cIEF, CZE, CE-SDS, DLS, MALS
Responsibilities
Drive PCA and MS strategy globally for a diverse biologics pipeline; Lead and develop a team of up to 5 associates; Manage resources, timelines, and project activities; Act as senior analytics expert in cross-functional project teams; Foster streamlined processes and innovation in characterization techniques.
Seniority
Principal, hands-on IC with people management