Senior Expert Science & Technology – Downstream Process Development
Core
Lead downstream process development for biopharmaceutical drug substance (DS) processes, focusing on purification of recombinant proteins at laboratory and pilot scale.
Role type
Senior Expert, hands-on IC process development scientist
Builds
Biopharmaceutical drug substance processes for late-phase development and market transfer
Domain
Biopharmaceuticals / Downstream Processing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Chromatography systems operation, Cross flow filtration, Tangential flow filtration, Membrane separation methods, Statistical discovery software, Regulatory CMC processes, Laboratory procedure generation, Project leadership, Scientific documentation, Troubleshooting
Preferred skills
Python, R, SQL programming
Technologies
ÄKTA systems, JMP, Electronic documentation systems
Responsibilities
Lead and organize downstream process development activities for portfolio pipeline projects; Perform chromatography and membrane separation methods for protein purification; Independently plan, perform, and document scientific experiments; Evaluate results and design next experiments; Generate scientific documents for internal/external partners and registration; Support technology transfers and define process steering controls; Generate lab procedures, reports, and SOPs; Act as Functional Lead for DSP development projects.
Seniority
Senior, hands-on IC
