Lead Scientist I（Purification）
Core
Lead purification science and chromatographic technology development for complex molecules (small molecules, oligonucleotides, ADCs, PROTACs) from discovery through scale-up.
Role type
Senior IC Lead Scientist (Purification)
Builds
Scalable purification processes and chromatographic methods for drug development programs
Domain
Biopharmaceuticals / CDMO / Chromatography
Required skills
Chromatographic separation design, Process scale-up, Technology transfer, Root-cause analysis, Scientific strategy, Modeling techniques
Preferred skills
ADC payload/linker purification, Peptide/oligonucleotide purification, Industrial CDMO experience, Automation implementation
Technologies
Preparative HPLC, Ion-exchange chromatography, Chiral chromatography, Flash chromatography, Modeling tools
Responsibilities
Design and optimize purification strategies for complex molecules, Develop scalable chromatographic solutions from mg to kg, Mentor junior scientists and lead technical discussions, Collaborate with chemists and engineers on process development, Evaluate emerging purification technologies and automation, Present scientific findings to governance committees
Seniority
Senior, hands-on IC with technical leadership
