Senior Scientist mRNA
Core
Design and optimize downstream purification processes for mRNA biologics to ensure high product quality, robustness, and manufacturability for GMP transfer.
Role type
Associate Principal Scientist (mRNA Process Development - Downstream)
Builds
Scalable mRNA purification processes and GMP-ready manufacturing protocols
Domain
Life Sciences / Biologics / mRNA
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
downstream process development, chromatography (affinity, ion exchange), tangential flow filtration (TFF), process scale-up, experimental design, data analysis, GMP manufacturing knowledge
Preferred skills
experience with nucleic acids or related biomolecules, multidisciplinary team collaboration
Technologies
chromatography systems, TFF equipment, analytical instrumentation
Responsibilities
Design and execute downstream purification experiments; optimize chromatography and filtration processes; analyze process data to improve yield and purity; support technology transfer to GMP manufacturing; document experimental work and communicate technical findings; collaborate with cross-functional teams on process development projects
Seniority
Senior, hands-on IC