Scientist I, Downstream Process Development - Biologics - Eurofins CDMO Alphora, Inc.
Core
Design and optimize purification and bioconjugation processes for therapeutic proteins and novel biologics, scaling processes toward larger-volume operations.
Role type
Scientist I, Downstream Process Development (Biologics)
Builds
Purification strategies and bioconjugation workflows for innovative therapeutics
Domain
Biopharmaceutical CDMO / Bioprocessing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Chromatography process design and execution, Tangential flow filtration (TFF) studies, Protein bioconjugation development, Aseptic techniques, Bioprocess engineering principles for scale-up, Filtration and clarification optimization, Design of Experiments (DoE), Quality by Design (QbD), Current Good Manufacturing Practices (cGMP), UNICORN control software proficiency
Preferred skills
Protein chemistry knowledge, Protein purification expertise
Technologies
UNICORN control software, TFF skids, Chromatography systems
Responsibilities
Design and execute laboratory studies for downstream processing steps, Perform hands-on laboratory execution from buffer preparation to purification runs, Draft and review technical documents including batch records and SOPs, Collaborate with cross-functional teams to advance projects and support equipment qualification, Independently plan, troubleshoot, and report on laboratory work, Assist in maintaining laboratory equipment and ordering consumables
Seniority
Entry-level Scientist I, hands-on IC with mentorship
