Senior Scientist, Tissue Culture
Core
Develop and characterize iPSC-derived cellular and disease models (mono-, co-, and tri-culture systems) and establish high-content imaging assays to support drug discovery and molecular evaluation.
Role type
Senior Scientist, Tissue Culture & High-Content Imaging
Builds
iPSC-derived cellular models, cell-based assays, and high-content imaging workflows for therapeutic evaluation
Domain
Biopharmaceuticals / Neuroscience / Cell Biology
Required skills
iPSC-derived cell model development, complex multicellular co- or tri-culture systems, high-content imaging (HCI) assay development, image acquisition optimization, quantitative data analysis, automated image-analysis pipelines, segmentation, classification, feature extraction, experimental design, troubleshooting biological/technical challenges
Preferred skills
Neuron/astrocyte/microglia co- or tri-culture experience, Revvity Operetta and Harmony platform expertise, CellProfiler/Spotfire/Prism usage, live-cell imaging, calcium imaging, MEA, flow cytometry, qRT-PCR, RNA-seq, immunocytochemistry
Technologies
Revvity Operetta, Revvity Harmony, CellProfiler, Spotfire, Prism
Responsibilities
Lead development and optimization of iPSC-derived cellular and disease models; Develop and optimize cell-based assays and phenotypic readouts; Lead the high-content imaging platform including experimental design and instrument optimization; Develop automated image-analysis pipelines; Provide training and technical support for HCI instrumentation; Independently design and execute experimental plans and interpret data
Seniority
Senior, hands-on IC
