Senior Scientist, Tissue Culture
Core
Develop and characterize iPSC-derived cellular and disease models (mono-, co-, and tri-culture systems) and establish cell-based assays to support drug discovery and biological evaluation.
Role type
Senior Scientist, Tissue Culture & High-Content Imaging
Builds
iPSC-derived cellular models, disease models, and high-content imaging assays for therapeutic evaluation
Domain
Biopharmaceuticals / Neuroscience / Cell Biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
iPSC-derived cell model development, complex multicellular system culture (neuron/astrocyte/microglia), high-content imaging (HCI) assay development, image acquisition optimization, quantitative data analysis, automated image-analysis pipeline development, experimental design, troubleshooting biological/technical challenges
Preferred skills
Revvity Operetta and Harmony platform expertise, CellProfiler/Spotfire/Prism usage, live-cell imaging, calcium imaging, MEA, flow cytometry, qRT-PCR, RNA-seq, immunocytochemistry/immunofluorescence, mentoring junior scientists
Technologies
Revvity Operetta, Harmony, CellProfiler, Spotfire, Prism
Responsibilities
Lead development and optimization of iPSC-derived cellular and disease models; Develop and optimize cell-based assays and phenotypic readouts; Lead the high-content imaging platform including experimental design and workflow development; Develop and optimize automated image-analysis pipelines; Provide training and technical support for HCI instrumentation; Independently design and execute experimental plans and interpret data
Seniority
Senior, hands-on IC
