Scientist II, Pharmaceutical Development
Core
Develop phase-appropriate analytical methods and execute preformulation studies for pre-FIH molecules to identify developability risks and support R&D decision-making in early drug development.
Role type
Scientist II, Pharmaceutical Development (Preformulation & Analytical Methods)
Builds
Preclinical and early clinical drug candidates for neurological, psychiatric, endocrine, and immunological disorders
Domain
Biopharmaceuticals / Pharmaceutical Development / Analytical Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Analytical method development, Preformulation sciences, Solubility analysis, Stability testing, Excipient compatibility assessment, Regulatory documentation authoring, Instrument operation (HPLC, LC-MS, DSC, TGA, PXRD, NMR, SEM), Data interpretation, Cross-functional collaboration
Preferred skills
LC-MS expertise, Agilent OpenLab software proficiency, Knowledge of specific dosage forms (SDD, HME, SEDDS), Cross-functional understanding of molecule selection
Technologies
HPLC (SEC, UV, MS, IEX), LC-MS, MS-MS, SEC-HPLC, DSC, TGA, PXRD, NMR, Particle-Size Analysis, GVS, PLM, SEM, OpenLab software
Responsibilities
Design and execute preformulation studies (thermodynamic/kinetic solubility, stability, compatibility), Develop fit-for-purpose analytical methods, Author regulatory submissions (INDs/CTAs/NDAs/BLAs) and technical reports, Research new instrumentation for development support, Present scientific findings to multidisciplinary teams
Seniority
Mid-level Scientist (4+ years experience required)
