Sr Scientist, Biologics Characterization
Core
Develop and deploy analytical methods and purification strategies to characterize therapeutic proteins and gene therapy vectors for late-stage development and commercialization.
Role type
Senior Scientist, Biologics Characterization
Builds
Analytical methods, purification protocols, and product characterization data for biologics pipeline
Domain
Biopharmaceuticals / Protein Science
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
protein separation, purification, tangential flow filtration (TFF), mass spectrometry, automated FPLC, HPLC (SEC, IEX, affinity), electrophoresis, spectroscopy, light scattering
Preferred skills
protein structure/function understanding, immunology/immunogenicity knowledge, biopharmaceutical industry experience
Technologies
FPLC, HPLC, SEC, IEX, affinity chromatography, capillary electrophoresis, microchip electrophoresis, SDS-PAGE, western blots
Responsibilities
Design and execute experiments to enrich, purify, and characterize protein variants; conduct biochemical/biophysical characterization for regulatory submissions; apply DOE and statistics to optimize methods; author technical documents and regulatory sections; maintain instruments and troubleshoot issues; mentor junior analysts
Seniority
Senior, hands-on IC with mentorship responsibilities
