Principal Scientist, Discovery Process Chemistry (DPC)
Core
Lead a team of scientists in the development of innovative solutions to complex chemistry problems across a diverse portfolio of projects and modalities in the discovery phase, from lead identification through candidate selection, to facilitate medicinal chemistry research by overcoming synthetic bottlenecks and streamlining SAR analogue synthesis.
Role type
Principal Scientist, Discovery Process Chemistry (DPC)
Builds
Novel chemical space and scalable synthetic routes for candidate compounds transitioning from discovery into early development
Domain
Pharmaceutical R&D, Organic/Process Chemistry
Required skills
Organic synthesis, Medicinal chemistry, Process chemistry, Bioconjugation, Computational chemistry, High-throughput experimentation (HTE), Inorganic synthesis, Organometallic chemistry, Structure based drug design, Synthetic chemistry, Preclinical research, Scientific publishing
Preferred skills
N/A
Technologies
N/A
Responsibilities
Lead a team of scientists in the development of innovative solutions to complex chemistry problems; Define scalable synthetic routes and successfully transition candidate compounds from discovery into early development; Manage supply of Active Pharmaceutical Ingredients (APIs) at varying scales; Provide broader mentorship and expertise across the DPC group; Remain current with the latest synthetic methodologies and drive innovation; Contribute to and lead cross-functional teams and influence team strategy and decision-making.
Seniority
Principal, hands-on IC with leadership