Associate Principal Scientist, Immunology Discovery
Core
Lead translational discovery activities using primary immune cell systems, ex vivo patient samples, and multi-omics datasets to build decision-enabling packages for target validation and candidate progression.
Role type
Senior IC Associate Principal Scientist (Immunology Discovery)
Builds
Translational packages supporting target prioritization, candidate progression, and patient selection
Domain
Biopharmaceuticals / Immunology / Autoimmunity
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Immunology, Cell Biology, Primary cell culture, Immune-cell assays, Co-culture systems, Tissue models, Ex vivo human sample platforms, Data interpretation, Experimental design
Preferred skills
Translational models of inflammatory/autoimmune disease, Flow cytometry, Cytokine profiling, Spatial biology, Transcriptomics, CRO coordination
Technologies
Flow cytometry, Multiplex tissue analysis, Spatial biology platforms, Transcriptomics tools
Responsibilities
Design and execute translational experiments to validate therapeutic targets; Develop disease-relevant in vitro and ex vivo models; Integrate mechanistic and pharmacology data to connect target biology with disease pathophysiology; Generate decision-enabling data packages; Mentor junior scientists; Collaborate with discovery biology, biomarker sciences, and clinical development teams
Seniority
Senior, hands-on IC with mentorship responsibilities
