Senior Director, Quantitative Pharmacology and Pharmacometrics – Immuno-Oncology
Core
Lead quantitative pharmacology and pharmacometrics strategies for oncology drug development, utilizing MIDD approaches to inform critical decisions on dose selection, trial design, and go/no-go milestones.
Role type
Senior Director, Group Leader (Strategy & Leadership)
Builds
Oncology drug development programs from post-preclinical candidate selection through registration
Domain
Biopharmaceuticals / Oncology / Quantitative Pharmacology
Deliverable
production ML models | dashboards & analysis | client delivery
Required skills
MIDD strategies, PK/PD modeling, oncology therapeutic knowledge, regulatory strategy authoring, team leadership, cross-functional collaboration, biomarker-driven dose selection, QSP/AI-ML application
Preferred skills
ADC/TCE modality experience, business development due diligence, regulatory agency interactions
Technologies
QSP, AI/ML, PK/PD modeling tools
Responsibilities
Lead quantitative pharmacology strategy across oncology programs; develop integrated MIDD strategies; lead and mentor a team of QP2 scientists; collaborate with Translational, Clinical, and Biostatistics teams; author and review regulatory documents (INDs, NDA/BLA); represent the company in regulatory agency interactions
Seniority
Senior Director, strategic leadership & team management