CareerPlan

Distinguished Scientist, Systems Toxicology

Cambridge, MA, USFull-time2026-11-04 → 2026-11-10
Hybrid

Core

Provide scientific leadership in applying multi-omics datasets and systems biology to predict safety liabilities, investigate mechanisms of toxicity, and assess human relevance in pharmaceutical drug development.

Role type

Distinguished Scientist (Senior, hands-on IC with global influence)

Builds

Robust analytical workflows for omics-based safety assessment and integrated biological analyses

Domain

Pharmaceutical biotechnology / Systems Toxicology / Multi-omics

Deliverable

production ML models

Required skills

Systems biology, Computational biology, Bioinformatics, Transcriptomics, Multi-omics integration, R, Python, Pathway analysis, Network biology, Hypothesis generation, Toxicological judgement

Preferred skills

Drug discovery experience, Strategic mindset, Cross-functional leadership

Technologies

R, Python, Bioinformatics tools

Responsibilities

Define approaches for applying omics to priority safety questions; Lead integrated analyses of complex biological datasets; Generate and prioritize mechanistic hypotheses; Establish reproducible and scalable analytical workflows; Drive cross-functional investigations across Preclinical Safety; Provide scientific leadership and mentorship across global functions

Seniority

Distinguished (Senior, hands-on IC with global influence)