CareerPlan

Protein ML Senior Principal Data Scientist

Waltham, MA, USFull-time$149k–$215k2026-10-27 → 2026-11-10
On-site

Core

Design and deploy state-of-the-art machine learning models to predict protein properties (immunogenicity, stability, manufacturability) and accelerate next-generation vaccine development.

Role type

Senior Principal IC Data Scientist (Protein ML)

Builds

Protein property prediction models and vaccine candidates

Domain

Biopharma / Computational Biology / AI

Deliverable

production ML models

Required skills

Protein language models, Python, PyTorch, AlphaFold, OpenFold, Boltz, ESM, SQL, R, Molecular dynamics, Deep mutational scanning

Preferred skills

Agentic tools (Claude Code), Immunogenicity predictors, Next-generation sequencing analysis

Technologies

PyTorch, AlphaFold, OpenFold, Boltz, ESM, Claude Code

Responsibilities

Develop protein property prediction models; Leverage foundational protein representations; Analyze protein sequence/structure/functional data; Collaborate with structural biology and bench lab teams; Maintain modeling codebase; Mentor colleagues on protein modeling tools

Seniority

Principal, hands-on IC with mentorship