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Senior Analytical Chemist - Solid State Characterization

Cambridge, MA💼 Full-time💰 $100,500–$100,500🗓 2026-07-10 → 2026-07-30

Core

Lead polymorphism and salt selection studies for synthetic molecules, acting as the solid-state representative on development projects to deploy solid-form selection strategies.

Role type

Senior IC analytical chemist (solid-state characterization)

Builds

Solid form selection strategies and analytical methods for transformative medicines

Domain

Pharmaceutical CMC development / Solid-state chemistry

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Polymorphism screening, Salt selection, XRPD, DSC, TGA, Crystal structure prediction, Technical reporting, Method development

Preferred skills

SEM, Raman, IR, Laser granulometry, Single-crystal growth, Crystallization processes, Crystallography expertise

Technologies

XRPD, DSC, TGA, SEM, Raman, IR, Laser granulometry, Computational crystal structure prediction tools

Responsibilities

Lead polymorphism studies including screening and thermodynamic assessment, Design and conduct salt selection studies, Act as solid-state representative on development projects, Develop and implement analytical methods using XRPD, DSC, TGA, SEM, Raman, IR, and laser granulometry, Provide physical characterization support to internal partner teams, Use computational tools for Crystal Structure Prediction studies, Generate technical reports independently, Introduce innovative analytical approaches including automation and AI/modeling integration

Seniority

Senior, hands-on IC

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