Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease Genomics
Core
Lead indication prioritization and expansion for Sanofi R&D assets by generating target trial emulation from large-scale EHR datasets and biobanks to understand disease trajectories.
Role type
Senior Principal Scientist (Real-World Evidence & Disease Genomics)
Builds
Strategic guidance for therapeutic program teams and reproducible evidence supporting the R&D pipeline
Domain
Biopharma / Epidemiology / Genomics
Deliverable
production ML models
Required skills
Longitudinal EHR analysis, OMOP common data models, Target trial emulation, Causal inference, GWAS methodology, Population-scale genomic analyses, Agentic AI frameworks, Cloud computing (AWS/GCP), Scalable analytical pipelines
Preferred skills
Experience with FinnGen/All of Us/UK Biobank, AI-assisted coding tools (Cursor/Claude Code), Cross-functional collaboration
Technologies
EHR foundation models, AWS, GCP, FinnGen, All of Us, UK Biobank, Cursor, Claude Code
Responsibilities
Lead indication prioritization and expansion for Sanofi R&D assets and external assets; Develop and implement methods for the analysis of longitudinal medical records; Define and champion well-curated disease cohorts and disease progression endpoints; Run genome-wide association studies (GWAS) in curated patient cohorts; Apply and scale methods across large population biobanks
Seniority
Senior, hands-on IC
