Principal Scientist Crystallization & Particle Engineering
Core
Lead the Crystallization & Particle Engineering Laboratory to drive innovative processes for Sanofi's small molecule portfolio from discovery to commercialization.
Role type
Principal Scientist / Scientific Leader
Builds
Innovative crystallization and particle engineering processes for small molecule APIs and drug products
Domain
Pharmaceutical R&D, Small Molecule Development
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Crystallization process development, Solid-state chemistry, Particle engineering (spray drying, milling, granulation), QbD, PAT, Polymorph identification, Process modeling and simulation, Team leadership, GMP compliance
Preferred skills
Experience from discovery to commercialization, Scientific publications/patents, Proprietary technology development, Advanced computational modeling
Technologies
XRPD, DSC, FTIR, Microscopy, Molecular dynamics, Thermodynamic modeling, Process simulation
Responsibilities
Define and implement laboratory scientific strategy, Drive development of crystallization processes, Explore new particle engineering methodologies, Lead and develop a team of 3-5 scientists, Ensure GMP compliance and validate processes, Collaborate with cross-functional teams globally
Seniority
Principal, hands-on IC with team leadership