Senior Scientist, Vector Attribute Sciences
Core
Technical leader for AAV and LVV analytical methods, developing and qualifying robust methods to characterize viral vector drug substances (identity, purity, potency, functional integrity) and defining Critical Quality Attributes (CQAs) for cell therapy programs.
Role type
Senior Scientist, Viral Vector Analytical Development
Builds
Viral vector drug substances (AAV/LVV) for next-generation cell therapy modalities
Domain
Biopharmaceuticals / Cell Therapy / Virology
Required skills
Virology (AAV/LVV), analytical method development and qualification, troubleshooting complex method/instrument issues, CQA strategy, regulatory documentation (S.3.1), mentoring technical teams
Preferred skills
Non-viral platform experience (RNP, RNA, LNP), automation and high-throughput analytical solutions
Technologies
qPCR, ddPCR, ELISA, potency/functional assays, capsid/particle characterization
Responsibilities
Lead method selection, development, and lifecycle management for AAV/LVV; troubleshoot and resolve complex method and instrument performance issues; develop and qualify analytical methods to characterize vector drug substances; mentor and coach scientists on method execution and troubleshooting; partner with process development, manufacturing, and CMC to resolve deviations; author and review SOPs and regulatory submission documents
Seniority
Senior, hands-on IC