Principal Scientist, Process Engineering
Core
Scale up and develop manufacturing processes for synthetic and antibody drug conjugate (ADC) drug substances to ensure safe, reliable production in clinical supply facilities.
Role type
Principal Scientist, Process Engineering (Chemical Process Development)
Builds
Clinical drug substance supplies for oncology, immunology, and cardiovascular disease treatments
Domain
Pharmaceutical manufacturing / Chemical Engineering
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Chemical engineering fundamentals (reaction, crystallisation, distillation, extraction, filtration, drying, milling), GMP manufacturing experience, scale-up risk assessment, hazardous chemistry handling, CDMO facility evaluation, technical negotiation, cross-functional leadership
Preferred skills
Lab-based small molecule development experience, specialty chemical or petrochemical industry background, international travel readiness
Technologies
GMP environments, CDMO facilities, hazardous chemical handling systems
Responsibilities
Review batch records for safety and operational feasibility, assess CDMO equipment and capabilities, troubleshoot manufacturing issues, present risk assessments to leadership, build relationships with global CDMO partners
Seniority
Principal, hands-on IC with mentorship responsibilities
