Senior Associate Scientist, In Vivo Pharmacology, Oncology Discovery Biology
Core
Conducting mouse in vivo pharmacology experiments and flow cytometry workflows to support early-stage oncology therapeutic development.
Role type
Senior Associate Scientist, In Vivo Pharmacology
Builds
Preclinical drug development programs for novel oncology therapeutics
Domain
Oncology / Immuno-oncology / Preclinical Research
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
mouse in vivo pharmacology experiments, tumor implantation (subcutaneous, orthotopic, chemically induced, GEMM, PDx), murine dosing (IV, IP, SC, PO, IT, IM), flow cytometry (panel design, multiparametric profiling), cell isolation (PBMC, T cells), cell culture, tissue harvesting and disaggregation, data analysis (GraphPad Prism), scientific documentation
Preferred skills
rodent surgical experience, orthotopic/chemically induced/GEMM/PDx models, intra-tumor/IM dosing, cytokine profiling (MSD/Luminex)
Technologies
GraphPad Prism, electronic lab notebooks, Microsoft Office, MSD, Luminex
Responsibilities
Conduct mouse in vivo pharmacology experiments including model development, tumor implantation, dosing, tumor measurements, health monitoring, and tissue sampling; Collaborate on in vivo efficacy and PK/PD studies; Execute end-to-end flow cytometry workflows including panel design, profiling, and data analysis; Isolate and functionally characterize PBMC and primary T cells; Maintain scientific documentation in electronic lab notebooks; Present research results to multidisciplinary teams
Seniority
Senior, hands-on IC
