Sr Scientist, Inflammation Biomarkers and Translational Research
Core
Lead end-to-end biomarker strategy for clinical programs from translational research through Phase I-III and registrational studies, defining pharmacodynamic and disease-monitoring biomarkers.
Role type
Senior Scientist, Translational Medicine & Biomarker Strategy
Builds
Clinical biomarker strategies, validated assays, and regulatory documentation for inflammatory and fibrotic disease therapies
Domain
Biopharmaceuticals, Immunology, Inflammation Biology, Translational Medicine
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Human immunology, assay qualification and validation, clinical trial design (Phase I-III), regulatory document authoring, cross-functional leadership, data integration (multi-omic, imaging), scientific publication
Preferred skills
Liver/gut biology and fibrotic mechanisms, health authority interaction (FDA/EMA), high-dimensional platforms (flow/mass cytometry, single-cell, spatial), data analysis (R, Python)
Technologies
R, Python, flow cytometry, mass cytometry, single-cell sequencing, spatial imaging, digital pathology
Responsibilities
Lead biomarker strategy for clinical programs; define and validate pharmacodynamic and prognostic biomarkers; oversee human-relevant translational studies; integrate multi-omic and clinical datasets; author regulatory documents; present data at conferences and meetings; mentor junior scientists
Seniority
Senior, hands-on IC with strategic leadership
