Principal Scientist, Vaccine Virology
Core
Lead research programs for seasonal and pandemic influenza vaccines, developing virology/immunology assays and preclinical studies to advance vaccine development.
Role type
Principal Scientist, Vaccine Virology & Immunology
Builds
Seasonal and pandemic influenza vaccines, respiratory-virus vaccine candidates
Domain
Biopharmaceuticals, Vaccine Development, Virology, Immunology
Required skills
Virology, Immunology, Assay development (neutralization, plaque, TCID50, RT-qPCR, reverse genetics), Preclinical study design (ferrets, rodents), Statistical analysis, Scientific leadership, Mentorship, Biosafety compliance
Preferred skills
Influenza HA/NA biology, Pseudovirus platforms (HIV-1/lentiviral, VSV), BSL-3 experience, Functional antibody assays (ADCC, ELISpot), Antigenic cartography, CRO oversight
Technologies
GraphPad Prism, R, Python
Responsibilities
Lead assigned vaccine research programs as a virology subject-matter expert; Design, develop, optimize, and troubleshoot virological and immunological assays; Design and interpret preclinical immunogenicity and protection studies using animal models; Apply rigorous experimental design and quantitative analysis to generate reproducible data; Provide scientific oversight of contract research organizations (CROs) and external collaborators; Mentor and train scientists and research associates; Conduct authorized laboratory research in BSL-2, enhanced BSL-2, and BSL-3 environments
Seniority
Principal, hands-on IC with strategic leadership