Study Physician- Neuroinflammation, Immunology Cell Therapy
Core
Lead a global, multi-cohort CAR-T cell therapy study for relapsing and progressive multiple sclerosis (MS), serving as the study-level medical authority for patient safety, dose-escalation decisions, and data interpretation.
Role type
Senior Study Physician (Neurology/Immunology)
Builds
Novel immune therapies for MS
Domain
Neuroimmunology / Cell Therapy / Clinical Trials
Required skills
Board certification in neurology, MS clinical experience, GCP knowledge, clinical study design, safety assessment (CRS, ICANS), data synthesis, clinical adjudication
Preferred skills
Biotech/pharma clinical development experience, CAR-T or cell therapy experience, early-phase/first-in-human study experience, international travel
Technologies
CAR-T, B-cell-depleting therapies, MRI, EDSS
Responsibilities
Own medical design and delivery of multi-cohort CAR-T study; Serve as medical monitor from eligibility through long-term follow-up; Lead safety assessment and governance including dose-escalation decisions; Review safety, efficacy, and biomarker data; Adjudicate complex MS events; Provide final medical review of protocols and results documents; Engage with investigators and regulatory bodies; Mentor colleagues on medical quality
Seniority
Senior, hands-on IC with matrix leadership