CareerPlan

Senior Principal Scientist Integrated Technology, Computation & Experimental Biology

US - California - South San FranciscoFull-time2026-11-02 → 2026-11-10

Core

Senior scientific and technology leader defining integrated strategies connecting human biology, computation, AI-enabled reasoning, preclinical models, and experimental testing to improve therapeutic discovery in inflammation research.

Role type

Senior Principal Scientist (Integrated Technology, Computation & Experimental Biology)

Builds

Integrated therapeutic discovery programs and scalable research capabilities for inflammation diseases

Domain

Biotechnology / Inflammation Research / Computational Biology / AI in Drug Discovery

Deliverable

production ML models

Required skills

Human-biology-led therapeutic hypothesis definition, AI-enabled analytical approaches (machine learning, agentic workflows), multi-omics data integration, experimental study design and analysis, cross-functional team leadership, emerging technology evaluation

Preferred skills

Inflammation/immunology/tissue biology expertise, human-relevant experimental systems design, drug discovery program advancement, scientific publication and patent generation

Technologies

Machine learning, agentic workflows, multi-omics, single-cell data, spatial data, high-content imaging, functional genomics, perturbational systems

Responsibilities

Lead cross-functional teams to deliver discovery results; define and execute integrated strategies for therapeutic discovery; synthesize literature and internal data to identify therapeutic mechanisms; design and direct rigorous experimental studies; identify and implement emerging technologies to scale research; mentor colleagues and communicate complex science to senior leadership

Seniority

Principal, strategy & mentorship