Project Toxicologist, Director – Oncology Targeted Delivery (OTD) Safety Science, Clinical Pharmacology and Safety Sciences (Cambridge, MA or Gaithersburg, MD)
Core
Lead toxicology strategies for novel oncology therapies (radioconjugates, ADCs, small molecules) to predict, assess, and mitigate safety risks from discovery to regulatory submission.
Role type
Director, Project Toxicologist (Oncology R&D)
Builds
Investigative toxicology programs and safety data supporting IND filings and development milestones.
Domain
Oncology drug discovery and development / Preclinical safety science
Required skills
Regulatory toxicology, Investigative toxicology, Radioconjugate expertise, ADC expertise, Translational safety (in vitro/in silico/in vivo), IND filing support, Cross-functional leadership, Scientific communication
Preferred skills
Radioconjugate experience, Small-molecule oncology therapeutics knowledge
Technologies
Organ-on-chip, Imaging, Omics
Responsibilities
Design and oversee regulatory and investigative toxicology programs; Apply toxicology expertise to anticipate clinical safety risks; Integrate emerging technologies to address complex safety questions; Present scientific conclusions to governance bodies; Maintain expertise in regulatory standards and preclinical safety; Provide strategic input for in-licensing and due diligence.
Seniority
Director, strategic leadership with hands-on scientific expertise