Senior Scientist, Vaccine Drug Product Development
Core
Design and develop vaccine formulations and drug product processes from early screening through clinical manufacturing readiness, focusing on multi-antigen/adjuvant combinations.
Role type
Senior Scientist, Vaccine Drug Product Development (via careerplan.io/jobs/R-258033-1-senior-scientist-vaccine-drug-product-development-at-astrazeneca)
Builds
Vaccine drug products (formulations and processes) for clinical development
Domain
Biopharmaceuticals / Vaccine Development
Required skills
Vaccine formulation development, In vitro characterization, Data interpretation and decision-making, Process engineering, Scientific communication, Collaboration
Preferred skills
Process scale-up and technology transfer, CMC and GMP familiarity, Regulatory authoring for IND/BLA, External scientific engagement
Technologies
DLS, HPLC/UPLC, LC-MS, UV/Fluorescence, ELISA, DSC/DMA, zeta potential, Karl Fischer, microfluidics, lyophilization
Responsibilities
Design and execute formulation studies for vaccine drug products, Perform experiments to evaluate formulation attributes, Design fit-for-purpose drug product processes and conduct scale-up studies, Author technical reports and CMC sections for regulatory filings, Represent Drug Product on CMC sub-teams, Present findings at internal forums and contribute to external publications
Seniority
Senior, hands-on IC
