Scientist III, Recombinant Protein Process Development
Core
Lead the development and optimization of microbial fermentation and recombinant protein expression processes for cytokines, growth factors, and related proteins.
Role type
Senior IC process development scientist (recombinant protein)
Builds
Upstream fermentation processes and integrated upstream/downstream workflows for therapeutic proteins
Domain
Biopharmaceuticals / Recombinant Protein Production
Required skills
microbial fermentation, recombinant protein expression, E. coli process development, bioreactor operation, process troubleshooting, experimental design, data analysis, protein purification principles, GMP documentation
Preferred skills
automated chromatography, protein refolding, integrated upstream/downstream optimization
Technologies
laboratory-scale bioreactors, chromatographic purification systems, SDS-PAGE, protein quantification assays
Responsibilities
Design and execute fermentation experiments to optimize protein yield and consistency; Operate and troubleshoot bioreactor systems; Collaborate with downstream teams to evaluate process impact on recovery and quality; Maintain GMP-compliant laboratory records and technical reports; Provide technical leadership and mentor less experienced scientists
Seniority
Senior, hands-on IC