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Sr. Pharmacometrician

💼 Full-time🗓 2026-09-24 → 2026-09-26

Core

Lead pharmacometric analyses and modeling to support drug development, including population PK/PD, exposure-response, and model-informed drug development strategies.

Role type

Senior Individual Contributor (Lead Pharmacometrician)

Builds

Production pharmacometric models, analysis plans, simulation strategies, and regulatory support documents for drug development programs.

Domain

Pharmaceutical/Biotechnology / Pharmacometrics and Model-Informed Drug Development

Deliverable

production ML models | product features

Required skills

Population PK/PD modeling, Exposure-response modeling, NONMEM, R programming, Model diagnostics, Simulation strategies, Regulatory document preparation, Project management, Technical mentoring

Preferred skills

Dose-response modeling, Biologics/Oncology experience, CAR-T program knowledge, Scientific publications

Technologies

NONMEM, R, Phoenix NLME, Monolix, Simcyp, GastroPlus, SDTM, ADaM

Responsibilities

Lead complex pharmacometrics projects and serve as senior reviewer; Develop and execute modeling strategies for dose selection and trial design; Perform hands-on modeling, simulation, and diagnostics using NONMEM and R; Create analysis plans and regulatory documents; Interpret quantitative results for clinical and regulatory audiences; Mentor team members and contribute to process improvements.

Seniority

Senior, hands-on IC with technical leadership

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