Scientist III, Upstream Process Development
Core
Design, plan, and execute upstream process development, scale-up, and technical transfer activities for gene therapy products from bench to pilot scale and cGMP manufacturing.
Role type
Senior IC upstream process development scientist (gene therapy)
Builds
Viral vector manufacturing processes and gene therapy products
Domain
Biopharmaceuticals / Gene Therapy / Upstream Processing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Aseptic technique, cell culture, stirred tank bioreactor operation, wave reactor operation, harvest and clarification operations, process development, scale-up, technical transfer, data analysis, technical writing, QbD knowledge
Preferred skills
Lentivirus upstream process development expertise, project management, training junior scientists
Technologies
Bioreactors, wave reactors, analytical instrumentation
Responsibilities
Design and execute experiments for tech transfer and scale-up; prepare development plans, batch records, SOPs, and summary reports; serve as project lead managing timelines and tasks; review data and collaborate on experimental design; train junior scientists
Seniority
Senior, hands-on IC