Lead Researcher - In Vivo & In Vitro Screening
Core
Lead in vitro and in vivo drug screening and mechanistic studies for pediatric leukemia and medulloblastoma therapies.
Role type
Senior Research Scientist (In Vivo & In Vitro Screening)
Builds
Novel therapeutic candidates and mechanistic insights for pediatric cancer treatments
Domain
Oncology / Pediatric Cancer Research / Translational Medicine
Required skills
Molecular biology, Cell culture, Flow cytometry, DNA/RNA isolation, Western blotting, Functional assays, Drug screening, Genomics, In vivo study design, Data analysis
Preferred skills
R&D methods, Lab project execution, High-risk leukemia research experience
Technologies
RNA sequencing (short-read, long-read), Cell-based assays, Primary and patient-derived cancer models
Responsibilities
Lead and perform in vitro and in vivo drug screening studies, Design and execute dose-response and combination therapy studies, Develop and optimize cell-based and molecular assays, Utilize genomics approaches to investigate therapeutic mechanisms, Analyze experimental data to prioritize candidates, Design and coordinate in vivo efficacy studies, Maintain comprehensive experimental records
Seniority
Senior, hands-on IC