Principal Computational Engineer
Core
Provide technical leadership and strategic vision for advanced computing environments and software ecosystems supporting life science research at St. Jude Children's Research Hospital.
Role type
Principal Computational Engineer (Senior IC with strategic leadership)
Builds
Scalable scientific computing solutions, HPC/cloud platforms, and data-intensive workflows for bioinformatics, genomics, and imaging research.
Domain
Life Sciences / High Performance Computing / Research Infrastructure
Deliverable
production ML models | infrastructure | product features
Required skills
HPC architecture, cloud computing, research software engineering, data-intensive workflow design, algorithm development, parallel programming (OpenMP, MPI, Pthreads), UNIX/Linux scripting, project management, team mentorship
Preferred skills
Bioinformatics pipeline support, HPC scheduler expertise (Slurm, LSF, Kubernetes), PhD in relevant field
Technologies
HPC clusters, Cloud platforms, Kubernetes, Slurm, LSF, OpenMP, MPI, Pthreads, UNIX/Linux
Responsibilities
Define and execute institutional research computing strategy; lead feasibility studies and implementation of new computational systems; oversee security and performance monitoring; guide technical management of data processing applications; mentor team members; engage with regulatory entities for patient data protection.
Seniority
Principal, hands-on IC with strategic oversight
