Scientist/Sr Scientist- Immunology
Core
Lead the spatial metabolomics and immunophenotyping platform at a children's research hospital, optimizing MALDI-MSI workflows and integrating multi-omics data to study immune and cancer metabolism.
Role type
Senior Scientist (IC) in spatial metabolomics and immunology
Builds
Spatial metabolomics datasets integrated with spatial transcriptomics and proteomics for immune/tumor microenvironment research
Domain
Biomedical research, immunology, cancer metabolism, spatial biology
Required skills
MALDI mass spectrometry imaging operation and troubleshooting, MSI data analysis, multi-omics data integration, immune or cancer metabolism expertise, experimental design, grant and manuscript drafting
Preferred skills
Experience with DESI imaging, multiplexed antibody imaging, computational methodologies for high-dimensional datasets
Technologies
MALDI-MSI, DESI, spatial transcriptomics platforms, multiplexed antibody imaging platforms
Responsibilities
Develop and oversee methods for mapping metabolites, lipids, and proteins in immune/tumor microenvironments; calibrate and maintain core MALDI/DESI imaging mass spectrometers; analyze and integrate complex spatial metabolomics datasets with multi-omics data; coordinate research projects and execute laboratory experiments; design and refine experimental approaches; draft sections of research manuscripts and grants; provide technical support and training for staff
Seniority
Senior, hands-on IC with significant leadership in platform operations