Cell Assay Senior Scientist - Blue Sky Kinases
Core
Senior scientist performing cell-based assays to validate structural findings and discover new kinase-mediated biology using molecular biology, biochemistry, and cell culture skills.
Role type
Senior IC cell biologist / cell assay scientist
Builds
Cell-based assays for kinase inhibitor validation and discovery of new kinase mechanisms
Domain
Biotechnology / Structural Biology / Oncology
Required skills
Cell culture, Protein kinase analysis, Phosphorylation-dependent signaling analysis, Cloning, PCR, qRT-PCR, Quantitative immunoassays, Flow cytometry, FACS, Western blotting, Immunoprecipitation, Microscopy, Statistical analysis
Preferred skills
Mouse models experience
Technologies
ELISA, AlphaLISA, Mesoscale Discovery, NanoBit assays, R scripts, Graphing software
Responsibilities
Research kinase-mediated signaling pathways and cellular outcomes; Identify appropriate cellular assays and cells for structure-guided analysis; Develop strategies for implementing cell-based and phenotypic assays; Optimize and troubleshoot cell-based assays; Perform statistical analysis; Interpret and communicate assay results
Seniority
Senior, hands-on IC