Postdoctoral Research Associate - Structural Biology – Scott Blanchard Lab
Core
Conduct single-molecule biophysical and computational studies to characterize GPCR structural dynamics and signaling mechanisms for drug discovery.
Role type
Postdoctoral Research Associate (Structural Biology)
Builds
Quantitative models explaining GPCR signaling mechanisms and high-quality publications.
Domain
Structural Biology / Biophysics / Drug Discovery
Deliverable
production ML models | research
Required skills
Molecular biology, biochemistry (membrane proteins), quantitative biophysical approaches, single-molecule analysis, experimental design, data analysis, hypothesis generation, scientific writing, oral presentation, mentoring
Preferred skills
GPCR signaling studies, single-molecule fluorescence analyses, isolation and functional characterization of GPCRs and signaling partners
Technologies
smFRET imaging, stopped-flow interrogation, single-molecule FRET
Responsibilities
Lead experimental design, execution, and data analysis of biophysical studies; Engineer and isolate high-quality GPCR samples; Perform smFRET imaging experiments and develop quantitative models; Work independently from hypothesis to publication; Collaborate in interdisciplinary multi-institutional groups; Train and mentor graduate students and postdocs
Seniority
Postdoctoral (0-3 years post-PhD)