Postdoctoral Research Fellow - Host-Pathogen Interactions & Host-Directed Therapeutics
Core
Lead research projects examining the interplay between host immune pathways and microbial pathogenesis to identify and validate novel host- and pathogen-directed therapeutic targets.
Role type
Postdoctoral Research Fellow (Host-Pathogen Interactions & Host-Directed Therapeutics)
Builds
Novel therapeutic strategies against infectious and malignant diseases
Domain
Microbiology, Immunology, Infectious Disease, Drug Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Bacterial culture and genetics, Molecular cloning, Mammalian cell culture, Flow cytometry, ELISA, Western blotting, Microscopy, Omics approaches (epigenomics, transcriptomics, proteomics), In vivo animal models, High-throughput screening assays, CRISPR-based gene editing, Primary cell culture, PBMC isolation
Preferred skills
Mycobacterium tuberculosis or Salmonella enterica serovar Typhimurium infection models, Manuscript and grant writing, Training and mentoring students
Technologies
CRISPR, Flow cytometry, ELISA, Western blotting, Confocal microscopy, Real-time PCR
Responsibilities
Conceptualize and execute experiments on host immune responses and bacterial pathogenesis, Perform molecular assays and high-throughput screening for drug discovery, Conduct in vivo animal model work, Analyze data and prepare figures/reports, Write manuscripts and grant applications, Train and mentor graduate and undergraduate students
Seniority
Postdoctoral Fellow, early-career researcher under supervision