Senior Director, Functional Genomics & Organoid Systems Biology
Core
Lead the wet lab component of a systems biology team to define and execute scientific strategies for patient-derived organoid (PDO) models, combining experimental validation with computational approaches to identify novel targets, biomarkers, and therapeutic strategies for cancer.
Role type
Senior Director, Functional Genomics & Organoid Systems Biology
Builds
An integrated discovery engine translating real-world clinico-genomic data into experimentally validated therapeutic opportunities using PDOs.
Domain
Precision medicine, oncology, functional genomics, organoid biology
Deliverable
production ML models | product features | research
Required skills
Cancer biology, functional genomics, target discovery, CRISPR-based screening, patient-derived organoids, ex vivo models, team leadership, budget management, strategic planning
Preferred skills
Translational oncology, drug discovery programs, next-generation functional assays, co-culture systems, immune components
Technologies
CRISPR, single-cell technologies, spatial technologies, computational biology tools
Responsibilities
Define long-term scientific strategy for functional screening; oversee design and execution of large-scale CRISPR and drug screening campaigns; establish rigorous experimental standards and reproducible workflows; partner with computational teams to prioritize hypotheses; build and mentor a multidisciplinary scientific team; manage departmental budgets and resource allocation.
Seniority
Senior Director, hands-on IC with substantial leadership experience
