Research Assistant II
Core
Generate large-scale, high-quality experimental data from human engineered heart tissues (EHTs) made from iPSC lines to train and validate predictive computational models for drug safety and efficacy.
Role type
Senior IC research scientist (stem cell biology & tissue engineering)
Builds
Digital twins of the human heart
Domain
Biomedical research, stem cell biology, tissue engineering, cardiac physiology
Deliverable
production ML models
Required skills
mammalian cell culture, iPSC culture and differentiation, cardiomyocyte handling, 3D tissue fabrication, functional assays (contractility, calcium imaging), multi-omic sample preparation, data management, genome editing support
Preferred skills
high-throughput workflow experience, pharmacology/compound screening, basic data analysis (R/Python), in vivo mouse studies
Technologies
iPSC lines, iPSC-CMs, multiwell formats, RNA-seq, single-cell assays
Responsibilities
Culture and differentiate iPSC lines; fabricate 3D EHTs and microtissues; perform functional assays on EHTs; prepare samples for multi-omic profiling; document experiments and manage data; support genome editing and in vivo validation; maintain lab supplies and train new members
Seniority
Senior, hands-on IC