Senior/Analytical Scientist (Method Development & Platform Innovation) – Contract position
Core
Lead development, optimization, and validation of bioassays and analytical methods for monoclonal antibodies and next-generation biologics to support quality and safety assessment.
Role type
Senior analytical scientist (method development & platform innovation)
Builds
Validated bioassays, analytical methods, and platform methods for physicochemical characterization of biologics
Domain
Biopharmaceuticals / Biologics / Analytical Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
cell-based bioassay design and execution, binding kinetics analysis (SPR/BLI), chromatographic techniques (SEC-HPLC, CEX-HPLC, HIC-HPLC), LC-HRMS protein characterization, ICH guideline compliance, ISO 17025/GLP/GMP laboratory operations
Preferred skills
antibody-drug conjugate (ADC) testing, bispecific antibody analysis, glycan profiling, post-translational modification analysis, biosimilar comparability assessment, AI/automation integration in lab workflows
Technologies
SPR, BLI, HRMS, SEC-HPLC, CEX-HPLC, HIC-HPLC
Responsibilities
Develop and validate bioassays for ADCC/CDC activity and cytotoxicity; develop analytical methods for binding interactions and structural characterization; lead platform method development for physicochemical characterization; prepare validation reports and SOPs; support laboratory accreditation and audits; provide expert scientific opinions to clients and stakeholders
Seniority
Senior, hands-on IC with leadership responsibilities
