Associate Director, Quantitative Systems Pharmacology
Core
Lead QSP modeling and simulation to support RNAi therapeutic drug development, focusing on dose selection, trial design, and mechanistic understanding of disease-treatment interactions.
Role type
Senior IC quantitative systems pharmacologist (Associate Director)
Builds
Production QSP models for drug development decisions
Domain
Biopharmaceuticals / Systems Pharmacology
Deliverable
production ML models
Required skills
QSP modeling and simulation, differential equation based modeling, parameter estimation/optimization, systems biology, pharmacokinetics, pharmacodynamics, statistical modeling, R, MATLAB, Simbiology
Preferred skills
mentoring, scientific publishing, cross-functional collaboration
Responsibilities
Strategize and execute QSP modeling for dose selection and trial design; Partner with clinical pharmacologists and modelers to interpret preclinical and clinical data; Build and utilize QSP models to understand disease pathways and treatment effects; Mentor team members and establish visibility of QSP modeling through publications and presentations; Explore synergy between QSP and other modeling approaches.
Seniority
Senior, hands-on IC with mentorship responsibilities