Senior Director, Biocatalysis
Core
Lead the discovery, engineering, development, and implementation of enzyme-enabled technologies for starting materials, oligonucleotides, and small molecule processes.
Role type
Senior Director, Biocatalysis
Builds
Scalable biocatalytic solutions for drug product and starting materials
Domain
Pharmaceutical biotechnology / Enzyme engineering
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Biocatalysis strategy definition, Protein discovery and engineering, Enzyme and reaction screening, Process development and scale-up, External collaboration management, Technical authority for biocatalysis
Preferred skills
None stated
Technologies
None stated
Responsibilities
Develop and lead the biocatalysis strategy across starting materials, oligonucleotides, and small molecule processes; Identify high-impact opportunities for biocatalyst substitution and new enzymatic chemistry; Lead enzyme discovery, engineering, screening, and optimization through internal capabilities and external partnerships; Establish internal protein screening and engineering capabilities; Drive biocatalytic applications for oligonucleotide synthesis and small molecule process development; Partner with Process Chemistry, CMC, Manufacturing, Quality, and Regulatory teams to translate biocatalytic concepts into scalable processes; Manage strategic collaborations with academic institutions, CROs/CDMOs, and enzyme discovery companies; Evaluate emerging technologies in biocatalysis and protein engineering; Serve as the technical authority for biocatalysis.
Seniority
Senior Director, strategy & mentorship