Director / Senior Director, DMPK
Core
Director of Drug Metabolism and Pharmacokinetics (DMPK) providing scientific and strategic leadership for in-licensing diligence and advanced preclinical/clinical program development.
Role type
Senior IC DMPK Director (Strategy & Execution)
Builds
Drug development programs for Formation Bio's portfolio of therapeutics
Domain
Biopharmaceuticals / Drug Discovery & Development
Required skills
DMPK expertise, ADME knowledge, human PK prediction, PK/PD analysis, regulatory strategy, CRO management, data evaluation, cross-functional leadership
Preferred skills
First-in-human experience, IND-enabling development, clinical translation, metabolism/transporter/DDI assessment
Technologies
Nonclinical and clinical PK datasets, exposure-response modeling, regulatory submission documents
Responsibilities
Evaluate nonclinical and clinical PK data for in-licensing opportunities; Develop DMPK strategies for preclinical and clinical-stage programs; Integrate ADME, toxicology, and clinical data to inform dose selection; Author or review regulatory submissions (INDs, CTAs); Provide scientific oversight of external CROs and consultants.
Seniority
Director, strategic leadership with hands-on technical execution