CareerPlan

Computational Chemist, Senior Principal Scientist

TokyoFull-time2026-10-26 → 2026-11-10

Core

Senior Principal Scientist leading computational chemistry and molecular modeling to advance drug discovery projects and materials exploration.

Role type

Senior Principal Scientist (Computational Chemist)

Builds

Drug discovery pipelines and materials exploration solutions

Domain

Life Sciences / Pharmaceutical R&D / Computational Chemistry

Deliverable

production ML models

Required skills

Virtual ligand screening, Lead optimization, AI/machine learning, Molecular dynamics, Quantum mechanics, Cheminformatics, ADMET/QSPR, Synthetic organic chemistry, Pharmacology, Toxicology, Programming/scripting

Preferred skills

Experience with chemically-aware databases, Cross-functional collaboration

Technologies

Schrödinger platform, Molecular modeling tools

Responsibilities

Lead active drug discovery projects, Develop and execute modeling strategies, Collaborate with global cross-functional teams, Present project updates to senior leadership, Mentor junior team members, Partner with software development teams to improve technologies