Director/Senior Director, In Vitro Biology & Molecular Pharmacology
Core
Direct strategy and execution for small molecule drug discovery programs, focusing on undrugged targets and novel hit finding approaches using in vitro biology and molecular pharmacology.
Role type
Senior Director, In Vitro Biology & Molecular Pharmacology
Builds
Novel therapeutics pipeline for biopharmaceutical and industrial clients
Domain
Biopharmaceutical drug discovery
Required skills
Drug discovery leadership, in vitro biology, molecular pharmacology, assay development, hit finding modalities (DEL, fragment screening, HTS/MTS, chemoproteomics), CRO management, strategic planning
Preferred skills
Protein degrader biology (PROTACs, molecular glues), LiveDesign platform, in vivo PK/PD study design
Technologies
DEL, fragment screening, HTS/MTS, chemoproteomics, LiveDesign
Responsibilities
Set strategic direction for In Vitro Biology across the Therapeutics Group portfolio; Assess target tractability and risk during target selection; Spearhead organization-wide hit finding strategy; Provide scientific oversight across multiple programs; Lead and develop the In Vitro Biology and Molecular Pharmacology team; Own the CRO strategy for In Vitro Biology
Seniority
Senior Director, strategic leadership with hands-on scientific oversight