CareerPlanSign in

Principal Site Reliability Engineer (we have office locations in Cambridge, Leeds and London)

London, England, gb💼 Full-time💰 $107,000–$107,000🗓 2026-09-25

Core

Establish and grow an organization-wide Site Reliability Engineering (SRE) capability, leading a small team to improve reliability across platforms and embed SRE principles into engineering squads.

Role type

Principal Site Reliability Engineer (Engineering Leader)

Builds

SRE team, reliability standards, tooling, and services that reduce operational toil

Domain

Healthcare genomics, bioinformatics pipelines, cloud infrastructure

Deliverable

production ML models | infrastructure | product features

Required skills

SRE principles and practices, software engineering (Python), system architecture resilience, platform engineering (CI/CD, IaC, monitoring), cloud platform experience, team leadership and mentorship

Preferred skills

Healthcare or bioinformatics background, regulated environment experience

Technologies

AWS, Python, NextFlow, Prefect, Dremio, Terraform, GitLab, Artifactory, DataDog, ECS, Fargate, Kubernetes, HPC

Responsibilities

Build and lead a small SRE team, identify high-value reliability opportunities, define standards and tooling, develop services to reduce toil, partner with product teams to embed SRE practices, influence engineering strategy and governance

Seniority

Principal, hands-on engineering leader with strategic scope

Sourced via smartrecruiters · Listed on CareerPlan, which tracks 70,000+ jobs from 20+ sources.