mRNA Process Development Senior Scientist
Core
Design, execute, and analyze experiments to develop, optimize, and scale GMP-compliant mRNA and plasmid DNA manufacturing processes.
Role type
Senior IC process development scientist (mRNA/biologics)
Builds
Scalable, robust, and well-characterized GMP processes for mRNA therapeutics and plasmid DNA production
Domain
Biopharmaceuticals / mRNA therapeutics / Gene editing
Required skills
mRNA process development, GMP process characterization, technology transfer, IVT process development, bioreactor/fermenter operation, chromatography (Cytiva AKTA Avant, Agilent 1260 HPLC/UHPLC), TFF, impurity profiling, data analysis for process optimization, GMP technical reporting
Preferred skills
Protein or AAV therapeutic process development, ELISA experience
Technologies
Cytiva AKTA Avant, Agilent 1260 HPLC/UHPLC, bioreactors/fermenters
Responsibilities
Design and execute experiments for mRNA process characterization; Evaluate process performance and identify productivity improvements; Support transition of development processes to GMP manufacturing; Operate and troubleshoot bioreactors and chromatography systems; Analyze data to support optimization and technology transfer; Author GMP-relevant technical reports and protocols
Seniority
Senior, hands-on IC
